Pharmacodynamics. Neurotropic vitamins of group B have a beneficial effect on inflammatory and degenerative diseases of the nerves and musculoskeletal system. They are prescribed to eliminate deficiency states, and in large doses have analgesic properties, improve blood circulation, normalize the functioning of the nervous system and the process of hematopoiesis.

Vitamin B1 is a very important active substance. In the body, it is phosphorylated to form biologically active thiamine diphosphate (cocarboxylase) and thiamine triphosphate (TTP).

Thiamine diphosphate as a coenzyme participates in important functions of carbohydrate metabolism, is of crucial importance in metabolic processes of nervous tissue, affects the conduction of nerve impulses in synapses. With a deficiency of vitamin B 1 in tissues, metabolites accumulate, primarily lactic and pyruvic acids, which leads to various pathological conditions and disorders of the nervous system.

Vitamin B6 in its phosphorylated form (pyridoxal-5?-phosphate – PALP) is a coenzyme of a number of enzymes that interact in the general non-oxidative metabolism of amino acids. Through decarboxylation, they are involved in the formation of physiologically active amines (e.g. adrenaline, histamine, serotonin, dopamine, tyramine), through transamination – in anabolic and catabolic metabolic processes (e.g. glutamate-oxaloacetate transaminase, glutamatepyruvate transaminase, GABA, ?-ketoglutarate transaminase), as well as in various processes of amino acid breakdown and synthesis. Vitamin B6 acts on 4 different sites of tryptophan metabolism. In the process of hemoglobin synthesis, vitamin B6 catalyzes the formation of ?-amino-?-ketoadenic acid.

Vitamin B12 is necessary for cellular metabolism. It affects the function of hematopoiesis (extrinsic an