Growing a Neem tree requires a warm and tropical climate. The tree is adaptable and can tolerate a wide range of soil conditions, although it thrives in well-drained, sandy soil. Neem trees are drought-tolerant and can withstand periods of water scarcity. They prefer full sun exposure for optimal growth.

Caring for a Neem tree involves regular watering, especially during the early stages of growth. Mature trees are relatively low-maintenance and can tolerate periods of drought. Pruning may be necessary to shape the tree and remove dead or damaged branches. Neem trees are generally resistant to pests and diseases.